By Heather Fullerton
The VIPS II study has been enrolling new pediatric stroke cases over the past three years with the aim of identifying the specific pathogens triggering childhood stroke; it will use next-generation sequencing of nucleic acids to identify pathogens in throat swabs and blood samples. We successfully obtained permission to continue enrolling in VIPS II through the COVID-19 pandemic, so might eventually know whether this new coronavirus, SARS CoV-2, is a trigger. In the meanwhile, we will be following the literature closely and blogging about relevant emerging evidence. Please let us know if you become aware of any COVID-related pediatric strokes, or new papers that we might have missed. And consider submitting an IPSO blog post yourself!
Links to Relevant Scientific Publications:
VIPS paper on clinical infections as a trigger for childhood stroke
VIPS paper on subclinical herpesvirus infection as a trigger for childhood stroke
Early publication on pernio-like lesions in children after COVID-19
Links to Relevant Lay Press Articles:
CNN Health article describing five young adults with COVID-19 related ischemic strokes at Mount Sinai Hospital in New York (April 23, 2020) https://www.cnn.com/2020/04/22/health/strokes-coronavirus-young-adults/index.html
Heather Fullerton, MD, MAS
UCSF Benioff Children's Hospital
Heather Fullerton, MD, MAS, is a pediatric vascular neurologist and Chief of Neurology at UCSF Benioff Children’s Hospital in San Francisco, California. She has been a member of the International Pediatric Stroke Study (IPSS) since 2002 and is the inaugural president of IPSO. She is grateful to everyone who has joined the IPSO effort and believes in the mission of improving the lives of children with cerebrovascular disease worldwide.